Our Research
Success

Grant Award – Kidscan Student Placement (2015 – 2016) Funding Award – £2000.00 Funding Awarded to – Dr Patricia Ragazzon Research Location – University of Salford Lead Researcher – Dr Patricia Ragazzon

Grant Award – Kidscan Pump Priming Grant (2016) Funding Award – £8000.00 Funding Awarded to – Dr Gemma Barron Research Location – Robert Gordon University Lead Researcher – Dr Gemma Barron

In the United Kingdom, approximately 3% of children have either a birth defect (congenital abnormality) and/or learning difficulties. Chromosomes are tiny structures within our cells that contain all our genetic information. The first line of…

HGF/SF is a growth factor involved in epithelial cell replication and motility which has been strongly implicated in cancer progression and metastasis.  It represents a potentially valuable extracellular target for therapeutic inhibition.  A series of…

Emetine is a naturally-occurring drug used for many years to treat amoebiasis (infection caused by amoeba’s). It also has very useful activity against many cancers including leukaemia but has side-effects which have prevented its development….

HGF/SF is a growth factor involved in epithelial cell replication and motility which has been strongly implicated in cancer progression and metastasis.  It represents a potentially valuable extracellular target for therapeutic inhibition.  Simple glycomimetics, based…

A number of compounds are known which bind to the colchicine binding site on tubulin, preventing the assembly of microtubules and thus preventing cancer cells from dividing. The project will establish methodologies for the synthesis…

Until recently, population-based techniques have dominated biomedical research, masking the meaningful heterogeneity present within a tumour, by ‘averaging out’ the detail [1]. We now know that this heterogeneity underpins resistance to treatment [2, 3] and…

Obese ALL patients have an increased risk of relapse and poorer event-free survival (10), the impact of which is made more complex by the correlation of corticosteroid therapy with rapid weight gain in children with…

Previous research, as described in the previous project, has identified existing anticancer properties of complex sugars from shellfish termed ‘glycosaminoglycans’ (GAGs). It is not known if they are effective just on leukaemia cells or if…

Assessing the effects of a new class of leukaemia drug on normal myeloid leukocytes and lymphocytes this includes neutrophils, monocytes, eosinophils, basophils, T-cells, B-cells and natural killer cells. The project will produce valuable data regarding…

ALL is the commonest cancer of childhood and treatment related toxicity and relapse are important therapeutic challenges. To further improve outcome new, non-toxic, targeted therapies need to be developed. These may be targeted to the…