Since established we have funded over 30 different research project. Some have led to breakthroughs including the development of novel treatments currently in pre-clinical trials
Every year over 60 children and teenagers in the UK are diagnosed with rhabdoymosarcoma (RMS), yet treatment regimes and survival rates have remained largely unchanged for decades. Radiotherapy is an important component of treatment for…
Find Out MoreThe development of ground-breaking technologies to facilitate the introduction of a new era of whole genome sequencing will revolutionise childhood leukaemia research and diagnosis. Whole genome sequencing has identified many genomic abnormalities of clinical relevance…
Find Out MoreIn childhood acute lymphoblastic leukemia (ALL), residual leukemic cells persisting in the bone marrow after the first 4 weeks of therapy are termed as minimal residual disease (MRD). These cells are presumed to resistant to…
Find Out MoreMedulloblastoma (MB) is the most common malignant brain tumour in children. More than one third of children with MB do not survive and essentially 100% of survivors face high risk of recurrence and significant long-term…
Find Out MoreObesity is recognised by the World Health Organisation as a global epidemic. Many links have been made between obesity and poorer outcomes for patients diagnosed with a range of diseases, including cancer. In particular, obese…
Find Out MoreNeuroblastoma is a very serious cancer, comprising around one tenth of childhood tumours, with around 15 cases in 100 being incurable. Neuroblastoma is unusual as depending on the age of patient diagnosis, cure rates differ…
Find Out MoreTreatments for acute lymphoblastic leukaemia (ALL) typically involve chemotherapy, usually in combination with steroids. There remains a need to develop novel therapies or enhance existing approaches to treatment, especially in patients with relapsed disease. A…
Find Out MoreLorem ipsum dolor sit amet, consectetur adipiscing elit. Nam cursus vel sem nec dictum. Cras finibus magna quis metus dignissim elementum. Proin vitae ornare felis, non dictum diam. Aliquam non erat enim. Vestibulum velit libero,…
Find Out MoreLorem ipsum dolor sit amet, consectetur adipiscing elit. Nam cursus vel sem nec dictum. Cras finibus magna quis metus dignissim elementum. Proin vitae ornare felis, non dictum diam. Aliquam non erat enim. Vestibulum velit libero,…
Find Out MoreLorem ipsum dolor sit amet, consectetur adipiscing elit. Nam cursus vel sem nec dictum. Cras finibus magna quis metus dignissim elementum. Proin vitae ornare felis, non dictum diam. Aliquam non erat enim. Vestibulum velit libero,…
Find Out MoreLorem ipsum dolor sit amet, consectetur adipiscing elit. Nam cursus vel sem nec dictum. Cras finibus magna quis metus dignissim elementum. Proin vitae ornare felis, non dictum diam. Aliquam non erat enim. Vestibulum velit libero,…
Find Out MoreThis project involves functional characterization of CALR mutations identified in the patient samples. The study will use FLAG tagged Calr protein to identify the sub-cellular localization of mutant Calreticulin. In addition using Co-IP technique it…
Find Out More
0161 295 3864 