Characterising biochemical changes in Atypical Teratoid Rhabdoid Tumour

ATRT is a highly malignant central nervous system (CNS) tumor which commonly affects children under 3?years of age. It clinically presents as 1%-2% of all paediatric central nervous system tumors and is reported to be the most common malignant CNS tumor in children under 6?months of age [1]. Treatment of this aggressive tumor represents a significant clinical challenge.Drug repurposing represents an alternative to conventional chemotherapy and involves the use of existing drugs for medical conditions they were not originally designed for. This project will explore drug-cell interactions for promising repurposing candidates using powerful modern analytical techniques of Infrared spectroscopy and Raman microspectroscopy which are capable of providing rich biochemical information.

Grant Award – Kidscan Student Placement (2019 – 2020)

Funding Award – £2000.00

Funding Awarded to – Dr Jo Denbigh

Research Location – University of Salford

Lead Researcher – Dr Jo Denbigh