JOSH'S STORY
In February of 2021, Josh’s parents noticed he was getting very pale. What was originally thought to...
Read MoreUntil recently, population-based techniques have dominated biomedical research, masking the meaningful heterogeneity present within a tumour, by ‘averaging out’ the detail [1]. We now know that this heterogeneity underpins resistance to treatment [2, 3] and that genetically identical cells have been shown to display different fates in response to the same drug, due to stochastic variation in relevant signaling pathways [3].
Tumours of the brain and nervous system, such as medulloblastoma (MB), are a leading cause of cancer-related death in infants and children [4]. The 5-year survival rate is 70%, although for patients with the most aggressive diagnosis, Group 3 (G3), this drops to 50% [6]. Also, the problem of debilitating late effects impacts on the quality of life of childhood cancer survivors. Over 60% of survivors develop chronic health conditions [5] such as peripheral neuropathy [6], which impacts on motor/sensory processes as a result of vincristine treatment.
Grant Award – Kidscan Student Placement (2017 – 2018)
Funding Award – £2000.00
Funding Awarded to – Dr Caroline Topham
Research Location – University of Salford
Lead Researcher – Dr Caroline Topham
In February of 2021, Josh’s parents noticed he was getting very pale. What was originally thought to...
Read MoreWhat a whopper of a night - Friday 20th May, our ambassador Isla's mum Jill and family hosted...
Read MoreWe want to say a huge thank you to Lee Mossop, former Captain of RFL Salford Red...
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