JOSH'S STORY
In February of 2021, Josh’s parents noticed he was getting very pale. What was originally thought to...
Read MoreHGF/SF is a growth factor involved in epithelial cell replication and motility which has been strongly implicated in cancer progression and metastasis. It represents a potentially valuable extracellular target for therapeutic inhibition. Simple glycomimetics, based on heparin, have been discovered with selective inhibitory activity against HGF/SF activation of its specific signalling receptor MET. Subsequently, an even simpler mimic has been made which shows good potency in a wound healing assay. The purpose of this project is to synthesise a series of simple heparin mimics for evaluation in wound-healing assays and to establish whether the wound healing inhibition is related to HGF-Met interaction and whether these compounds have potential in cancer chemotherapeutics.
Grant Award – Kidscan Student Placement (2016 – 2017)
Funding Award – £2000.00
Funding Awarded to – Dr Jim Wilkinson
Research Location – University of Salford
Lead Researcher – Dr Jim Wilkinson
In February of 2021, Josh’s parents noticed he was getting very pale. What was originally thought to...
Read MoreWhat a whopper of a night - Friday 20th May, our ambassador Isla's mum Jill and family hosted...
Read MoreWe want to say a huge thank you to Lee Mossop, former Captain of RFL Salford Red...
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