ATRT is a highly malignant central nervous system (CNS) tumour which commonly affects children under 3 years of age. It clinically presents as 1%-2% of all paediatric central nervous system tumours and is reported to be the most common malignant CNS tumour in children under 6 months of age.
Treatment of this aggressive tumour represents a significant clinical challenge. Drug repurposing represents an alternative to conventional chemotherapy and involves the use of existing drugs for medical conditions they were not originally designed for.
This project will explore drug-cell interactions for promising repurposing candidates using powerful modern analytical techniques of Infrared spectroscopy and Raman microspectroscopy which are capable of providing rich biochemical information.
Grant Award – Studentship 2019-2020
Funding Award – £2000
Funding Awarded to – Dr Jo Denbigh
Research Location – University of Salford
Lead Researcher – Dr Jo Denbigh