Newcastle University
Current Position
Aug 2020 – present: Lecturer in Haemato-oncology, Newcastle University
Previous positions
Aug 2015-July 2020: Newcastle University Research Fellow, Newcastle University
June 2015-June 2018: John Goldman Fellow, Leuka, Newcastle University
Feb 2001-Aug 2015: Kay Kendall Leukaemia Fund Intermediate Research Fellow, Newcastle University
April 2008- Feb 2011: Research Associate, Newcastle University
December 2006-March 2008: Postdoctoral Scientist, University of Southampton
April 2008-January 2011: Research Associate, Newcastle University
Memberships
British Society of Haematology since 2008
Manuscript/Grant Peer Review
Journals: Blood, British Journal of Haematology, Leukaemia, Clinical Epigenetics and Haematologica
Funding bodies: MRC, Cure Kids, Wellcome Trust Indian Alliance Fellowship Scheme.
Boards and Committees
Editorial Board Member for Scientific Reports, a journal from Nature Publishing Group since February 2015
Newcastle University Research Career Development Group
NICR Teaching and Training Committee
Co-lead for the Newcastle University Centre for Cancer Fellowship and Grants Committee
Research Interests
The characterisation of genomic abnormalities that drive the development of haematological malignancies has progressed significantly over the past 40 years. One major advance has been the link between genetic abnormalities and outcome. My research has provided two such examples highlighting that rearrangements involving the immunoglobulin loci (Ig) and the cytokine receptor CRLF2 are associated with a poor outcome. These findings have led to treatment changes within the United States and are currently being used to inform the next paediatric and adult ALL treatment trials within the UK.
I am known within the field of leukaemia research for characterising novel and recurrent translocations involving the Ig loci. My future research goals are to increase the molecular understanding of both CRLF2 and Ig driven malignancies.
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