JOSH'S STORY
In February of 2021, Josh’s parents noticed he was getting very pale. What was originally thought to...
Read MoreThe novel terpenoid (-)-hispidospermidin 1 was isolated from a strain of Chaetosphaeronema hispidulum (Cda) Moesz NR 7127. Reported in 1994, its structure was determined by both NMR studies of 1 and x-ray crystallographic analysis of the (1S)-(+)-10-camphosulphonic acid salt 2 (fig. 1). It was found to comprise a tetracyclic cage with a pendant N,N-trimethylated spermidine side chain. (-)-Hispidospermidin was found to be a potent and specific inhibitor of the enzyme phospholipase C (PLC) with and IC50 of 16µM (rat brain PLC). In this regard, the parent compound or analogues can be considered excellent targets for novel therapeutic agents in cancer trials within the Kidscan environment.
Grant Award – Kidscan Student Placement (2017 – 2018)
Funding Award – £1000.00
Funding Awarded to – Dr Stephen Rossington
Research Location – University of Salford
Lead Researcher – Dr Stephen Rossington
In February of 2021, Josh’s parents noticed he was getting very pale. What was originally thought to...
Read MoreWhat a whopper of a night - Friday 20th May, our ambassador Isla's mum Jill and family hosted...
Read MoreWe want to say a huge thank you to Lee Mossop, former Captain of RFL Salford Red...
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