fbpx
LATEST NEWS

How the Human Genome Project transformed Cancer Research

Each year, National DNA day marks the date that the Human Genome Project was completed. To mark the anniversary, we take a look at why the Human Genome Project was so monumental for Cancer Research, and how it has helped to propel us forward in the quest to find safer and more precise treatments for children’s cancer.

What is DNA exactly?
DNA is the blueprint for building a human being and is basically a long code made up of a combination of 4-chemicals, or bases that can be abbreviated as the letters, A,T,G and C. This short alphabet exists in varied patterns or combinations, which can be grouped together into units that we know as genes. This combination of letters (chemicals) within a gene, defines exactly how you will look, develop and function throughout your life.

The Human Genome Project
Deciphering DNA has always proven to be extremely complicated because the combination of letters that define certain traits don’t just sit in one single gene. Initiated in 1990, the 15-year Human Genome Project set out to provide a map of the human genome. On completion, it gave scientists the ability to read the entire, and unique, combination of letters in a person’s DNA code.

But how does the ability to read a person’s DNA code link to cancer research?
By comparing a sample of DNA from a patients cancerous cells – to the map produced by the human genome project – scientists can now identify the exact cause of an individual’s cancer.

And, thanks to recent advances in the speed that scientists can now read a patients DNA code – they have now been able to identify exactly how many mutations in a cell’s DNA code are required for a cell to become cancerous, in a number of cancer types.

Studies like this on large numbers of patients, along with the results of the Human Genome Project have truly propelled cancer research. By understanding which mutations caused cancer to occur in a particular patient, scientists can now explore the use of techniques such as gene therapy, gene editing and other treatments that target specifically the cause of the cancer based on the patients’ DNA code.

These precision therapies are one of the most exciting developments in children’s cancer research – in the future it will be possible to treat cancer without causing lifelong side-effects of standard treatments such as chemotherapies, that blight the lives of more than two thirds of childhood cancer survivors.

Grand National Sweepstake

Grand National Sweepstake

One of the most famous Horse Races of the year is here again, and what better way...

Read More

Cooking up a cure for extremely rare types of children’s...

Cooking up a cure for extremely rare types of children’s...

We have all been there, we go to visit the doctors, they listen to your symptoms, conduct...

Read More

Kidscan welcomes Guest Speaker Sarah Collins

Kidscan welcomes Guest Speaker Sarah Collins

Since December 2018 The Grill on New York Street has been hosting a quarterly networking lunch in...

Read More

Newsletter Sign Up