An immuno-chermotherapy in confined nanospace for the treatment of pediatric cancer

Exploring the use of Nanotechnology for targeted immunotherapy of Neuroblastoma

Cancer occurs when our cells mutate and rapidly divide, so traditional chemotherapy are designed to attack rapidly dividing cells. However, in children many healthy cells are also rapidly dividing as they grow, so chemotherapies can cause damage to their bodies normal tissues. This damage usually  leads to late-effects including organ and bone problems, developmental issues, hearing loss and infertility.

At the University of Salford, researchers are looking for ways to use metal organic framework (MOFs) nanotechnologies, to encase chemotherapy drugs until they reach the site of the cancer. In doing so they hope to stop the damage that chemotherapies do to healthy cells within the body, whilst targeting the hard to treat cancers. This project aims to explore the use of MOFs with existing chemotherapy drugs to treat Neuroblastoma.

Project Title: An immuno-chermotherapy in confined nanospace for the treatment of pediatric cancer
Grant Award – Project is currently under review
Funding Award – £2,000
Research Location – University of Salford
Lead Researcher – Dr. Rosa Arrigo

This project is currently under review. Project details will be published once project is funded.